Genotype distribution-based inference of collective effects in genome-wide association studies: insights to age-related macular degeneration disease mechanism

BACKGROUND: Genome-wide association studies provide important insights to the genetic component of disease risks. However, an existing challenge is how to incorporate collective effects of interactions beyond the level of independent single nucleotide polymorphism (SNP) tests. While methods consider...

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Veröffentlicht in:BMC Genomics
Hauptverfasser: Woo, Hyung Jun, Yu, Chenggang, Kumar, Kamal, Gold, Bert, Reifman, Jaques
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Methodology Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5006276/
https://ncbi.nlm.nih.gov/pubmed/27576376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2871-3
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