Genotype distribution-based inference of collective effects in genome-wide association studies: insights to age-related macular degeneration disease mechanism

BACKGROUND: Genome-wide association studies provide important insights to the genetic component of disease risks. However, an existing challenge is how to incorporate collective effects of interactions beyond the level of independent single nucleotide polymorphism (SNP) tests. While methods consider...

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Bibliografische gegevens
Gepubliceerd in:BMC Genomics
Hoofdauteurs: Woo, Hyung Jun, Yu, Chenggang, Kumar, Kamal, Gold, Bert, Reifman, Jaques
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2016
Onderwerpen:
Methodology Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5006276/
https://ncbi.nlm.nih.gov/pubmed/27576376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2871-3
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