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Time-varying SMART design and data analysis methods for evaluating adaptive intervention effects

BACKGROUND: In a standard two-stage SMART design, the intermediate response to the first-stage intervention is measured at a fixed time point for all participants. Subsequently, responders and non-responders are re-randomized and the final outcome of interest is measured at the end of the study. To...

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Detalhes bibliográficos
Publicado no:BMC Med Res Methodol
Main Authors: Dai, Tianjiao, Shete, Sanjay
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5006275/
https://ncbi.nlm.nih.gov/pubmed/27578254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12874-016-0202-7
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