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ScaffoldScaffolder: solving contig orientation via bidirected to directed graph reduction

Motivation: The contig orientation problem, which we formally define as the MAX-DIR problem, has at times been addressed cursorily and at times using various heuristics. In setting forth a linear-time reduction from the MAX-CUT problem to the MAX-DIR problem, we prove the latter is NP-complete. We c...

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Bibliografske podrobnosti
izdano v:Bioinformatics
Main Authors: Bodily, Paul M., Fujimoto, M. Stanley, Snell, Quinn, Ventura, Dan, Clement, Mark J.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5006237/
https://ncbi.nlm.nih.gov/pubmed/26382194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btv548
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