Downregulation of interleukin 8 gene expression in human fibroblasts: unique mechanism of transcriptional inhibition by interferon.

The chemotactic cytokine interleukin 8 (IL-8) is produced upon stimulation by various agents in many cell types, including connective-tissue fibroblasts. Tumor necrosis factor (TNF) and IL-1 are potent inducers of IL-8 expression. Earlier we showed that TNF-induced stimulation of IL-8 mRNA accumulat...

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Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Oliveira, I C, Sciavolino, P J, Lee, T H, Vilcek, J
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 1992
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50062/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1409601/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.19.9049
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