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Hypermetabolism and hypercatabolism of skeletal muscle accompany mitochondrial stress following severe burn trauma

Burn trauma results in prolonged hypermetabolism and skeletal muscle wasting. How hypermetabolism contributes to muscle wasting in burn patients remains unknown. We hypothesized that oxidative stress, cytosolic protein degradation, and mitochondrial stress as a result of hypermetabolism contribute t...

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Bibliografske podrobnosti
izdano v:Am J Physiol Endocrinol Metab
Main Authors: Ogunbileje, John O., Porter, Craig, Herndon, David N., Chao, Tony, Abdelrahman, Doaa R., Papadimitriou, Anastasia, Chondronikola, Maria, Zimmers, Teresa A., Reidy, Paul T., Rasmussen, Blake B., Sidossis, Labros S.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5005969/
https://ncbi.nlm.nih.gov/pubmed/27382037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00535.2015
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