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Hypermetabolism and hypercatabolism of skeletal muscle accompany mitochondrial stress following severe burn trauma

Burn trauma results in prolonged hypermetabolism and skeletal muscle wasting. How hypermetabolism contributes to muscle wasting in burn patients remains unknown. We hypothesized that oxidative stress, cytosolic protein degradation, and mitochondrial stress as a result of hypermetabolism contribute t...

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Detalhes bibliográficos
Publicado no:Am J Physiol Endocrinol Metab
Main Authors: Ogunbileje, John O., Porter, Craig, Herndon, David N., Chao, Tony, Abdelrahman, Doaa R., Papadimitriou, Anastasia, Chondronikola, Maria, Zimmers, Teresa A., Reidy, Paul T., Rasmussen, Blake B., Sidossis, Labros S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5005969/
https://ncbi.nlm.nih.gov/pubmed/27382037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00535.2015
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