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Chronic adjunction of 1-deoxynojirimycin protects from age-related behavioral and biochemical changes in the SAMP8 mice

Several studies have indicated that a caloric restriction mimetic or treatment for type 2 diabetes may reverse brain aging. Therefore, we investigated the effect of 1-deoxynojirimycin (DNJ), an alkaloid acting as an inhibitor of α-glucosidase, on age-related behavioral and biochemical changes. SAMP8...

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Detalhes bibliográficos
Publicado no:Age (Dordr)
Main Authors: Chen, Gui-Hai, Tong, Jing-Jing, Wang, Fang, Hu, Xue-Qin, Li, Xue-Wei, Tao, Fei, Wei, Zhao-Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5005858/
https://ncbi.nlm.nih.gov/pubmed/26400487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-015-9839-0
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