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Transient tissue-scale deformation coordinates alignment of planar cell polarity junctions in the mammalian skin

Planar cell polarity (PCP) refers to the collective alignment of polarity along the tissue plane. In skin, the largest mammalian organ, PCP aligns over extremely long distances but the global cues that orient tissue polarity are unknown. Here we show that Celsr1 asymmetry arises concomitant with a g...

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Bibliographic Details
Published in:Curr Biol
Main Authors: Aw, Wen Yih, Heck, Bryan W., Joyce, Bradley, Devenport, Danelle
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5005808/
https://ncbi.nlm.nih.gov/pubmed/27451904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2016.06.030
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