‘Get in Early’; Biofilm and Wax Moth (Galleria mellonella) Models Reveal New Insights into the Therapeutic Potential of Clostridium difficile Bacteriophages

Clostridium difficile infection (CDI) is a global health threat associated with high rates of morbidity and mortality. Conventional antibiotic CDI therapy can result in treatment failure and recurrent infection. C. difficile produces biofilms which contribute to its virulence and impair antimicrobia...

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Bibliographic Details
Published in:Front Microbiol
Main Authors: Nale, Janet Y., Chutia, Mahananda, Carr, Philippa, Hickenbotham, Peter T., Clokie, Martha R. J.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2016
Subjects:
Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5005339/
https://ncbi.nlm.nih.gov/pubmed/27630633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2016.01383
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