Post-transcriptional Regulation of BRCA2 through Interactions with miR-19a and miR-19b

Breast cancer type 2, early onset susceptibility gene (BRCA2) is a major component of the homologous recombination DNA repair pathway. It acts as a tumor suppressor whose function is often lost in cancers. Patients with specific mutations in the BRCA2 gene often display discrete clinical, histopatho...

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Bibliografiske detaljer
Udgivet i:Front Genet
Main Authors: Mogilyansky, Elena, Clark, Peter, Quann, Kevin, Zhou, Honglei, Londin, Eric, Jing, Yi, Rigoutsos, Isidore
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2016
Fag:
Genetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5005319/
https://ncbi.nlm.nih.gov/pubmed/27630665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2016.00143
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