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Three-Dimensional Compound Comparison Methods and Their Application in Drug Discovery

Virtual screening has been widely used in the drug discovery process. Ligand-based virtual screening (LBVS) methods compare a library of compounds with a known active ligand. Two notable advantages of LBVS methods are that they do not require structural information of a target receptor and that they...

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Publicat a:Molecules
Autors principals: Shin, Woong-Hee, Zhu, Xiaolei, Bures, Mark Gregory, Kihara, Daisuke
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5005041/
https://ncbi.nlm.nih.gov/pubmed/26193243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules200712841
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