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Identifying protein aggregation mechanisms and quantifying aggregation rates from combined monomer depletion and continuous scattering
Parallel temperature initial rates (PTIR) from chromatographic separation of aggregating protein solutions are combined with continuous simultaneous multiple sample light scattering (SMSLS) to make quantitative deductions about protein aggregation kinetics and mechanisms. PTIR determines the rates a...
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Publicado no: | Anal Biochem |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5004974/ https://ncbi.nlm.nih.gov/pubmed/27510552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2016.08.002 |
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