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Direct lineage reprogramming via pioneer factors; a detour through developmental gene regulatory networks
Although many approaches have been employed to generate defined fate in vitro, the resultant cells often appear developmentally immature or incompletely specified, limiting their utility. Growing evidence suggests that current methods of direct lineage conversion may rely on the transition through a...
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| Publicado no: | Development |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Ltd
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5004913/ https://ncbi.nlm.nih.gov/pubmed/27486230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.138263 |
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