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Cadherin-11 is a novel regulator of extracellular matrix synthesis and tissue mechanics

We discovered that Cadherin-11 (CDH11) regulates collagen and elastin synthesis, both affecting the mechanical properties and contractile function of animal tissues. Using a Cdh11-null mouse model, we observed a significant reduction in the mechanical properties [Youngs' modulus and ultimate te...

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Bibliographic Details
Published in:J Cell Sci
Main Authors: Row, Sindhu, Liu, Yayu, Alimperti, Stella, Agarwal, Sandeep K., Andreadis, Stelios T.
Format: Artigo
Language:Inglês
Published: The Company of Biologists Ltd 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004872/
https://ncbi.nlm.nih.gov/pubmed/27311482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.183772
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