Mice Survival and Plasmatic Cytokine Secretion in a “Two Hit” Model of Sepsis Depend on Intratracheal Pseudomonas Aeruginosa Bacterial Load

Sepsis is characterized by pro- and anti-inflammatory responses following infection. While inflammation is responsible for widespread organ damage, anti-inflammatory mediators lead to immunoparalysis increasing susceptibility to secondary infections (nosocomial pneumonia). We aimed to investigate th...

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Publicat a:PLoS One
Autors principals: Restagno, Damien, Venet, Fabienne, Paquet, Christian, Freyburger, Ludovic, Allaouchiche, Bernard, Monneret, Guillaume, Bonnet, Jeanne-Marie, Louzier, Vanessa
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004855/
https://ncbi.nlm.nih.gov/pubmed/27574993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162109
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