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Inositol polyphosphate receptor and clathrin assembly protein AP-2 are related proteins that form potassium-selective ion channels in planar lipid bilayers.

We have previously described an inositol polyphosphate receptor (IPxRec), purified from detergent-solubilized bovine cerebellum microsomes, that displays potassium ion channel activity in planar lipid bilayers. We now find that the IPxRec is closely related to clathrin assembly protein AP-2. The IPx...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Timerman, A P, Mayrleitner, M M, Lukas, T J, Chadwick, C C, Saito, A, Watterson, D M, Schindler, H, Fleischer, S
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1992
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50047/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1329085/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.19.8976
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