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Association between EZH2 expression, silencing of tumor suppressors and disease outcome in solid tumors
EZH2, the main catalytic component of the Polycomb Repressive Complex 2 (PRC2) is apparently upregulated in most solid tumors. Furthermore its expression generally associates with poor prognosis. It was proposed that this correlation reflects a causal event, EZH2 mediating the silencing of key tumor...
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| Yayımlandı: | Cell Cycle |
|---|---|
| Asıl Yazarlar: | , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Taylor & Francis
2016
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5004685/ https://ncbi.nlm.nih.gov/pubmed/27419533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1208872 |
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