Nfib promotes Metastasis through a Widespread Increase in Chromatin Accessibility

Metastases are the main cause of cancer deaths, but the mechanisms underlying metastatic progression remain poorly understood. We isolated pure populations of cancer cells from primary tumors and metastases from a genetically engineered mouse model of human small cell lung cancer (SCLC) to investiga...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Denny, Sarah K., Yang, Dian, Chuang, Chen-Hua, Brady, Jennifer J., Lim, Jing Shan, Grüner, Barbara M., Chiou, Shin-Heng, Schep, Alicia N., Baral, Jessika, Hamard, Cécile, Antoine, Martine, Wislez, Marie, Kong, Christina S., Connolly, Andrew J., Park, Kwon-Sik, Sage, Julien, Greenleaf, William J., Winslow, Monte M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004630/
https://ncbi.nlm.nih.gov/pubmed/27374332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.05.052
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