An siRNA screen for ATG protein depletion reveals the extent of the unconventional functions of the autophagy proteome in virus replication

Autophagy is a catabolic process regulated by the orchestrated action of the autophagy-related (ATG) proteins. Recent work indicates that some of the ATG proteins also have autophagy-independent roles. Using an unbiased siRNA screen approach, we explored the extent of these unconventional functions...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Mauthe, Mario, Langereis, Martijn, Jung, Jennifer, Zhou, Xingdong, Jones, Alex, Omta, Wienand, Tooze, Sharon A., Stork, Björn, Paludan, Søren Riis, Ahola, Tero, Egan, Dave, Behrends, Christian, Mokry, Michal, de Haan, Cornelis, van Kuppeveld, Frank, Reggiori, Fulvio
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004442/
https://ncbi.nlm.nih.gov/pubmed/27573464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201602046
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