Multiciliated cell basal bodies align in stereotypical patterns coordinated by the apical cytoskeleton

Multiciliated cells (MCCs) promote fluid flow through coordinated ciliary beating, which requires properly organized basal bodies (BBs). Airway MCCs have large numbers of BBs, which are uniformly oriented and, as we show here, align linearly. The mechanism for BB alignment is unexplored. To study th...

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Veröffentlicht in:J Cell Biol
Hauptverfasser: Herawati, Elisa, Taniguchi, Daisuke, Kanoh, Hatsuho, Tateishi, Kazuhiro, Ishihara, Shuji, Tsukita, Sachiko
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2016
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Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004441/
https://ncbi.nlm.nih.gov/pubmed/27573463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201601023
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