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New and emerging prognostic and predictive genetic biomarkers in B-cell precursor acute lymphoblastic leukemia

Acute lymphoblastic leukemia (ALL) is a heterogeneous disease at the genetic level. Chromosomal abnormalities are used as diagnostic, prognostic and predictive biomarkers to provide subtype, outcome and drug response information. t(12;21)/ETV6-RUNX1 and high hyper-diploidy are good-risk prognostic b...

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Detalhes bibliográficos
Publicado no:Haematologica
Autor principal: Moorman, Anthony V.
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004393/
https://ncbi.nlm.nih.gov/pubmed/27033238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2015.141101
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