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Synthesis and biological evaluation of kibdelone C and simplified derivatives
Poylcyclic tetrahydroxanthones comprise a large class of cytototoxic natural products. No mechanism of action has been described for any member of the family. We report the synthesis of kibdelone C and several simplified analogs. Both enantiomers of kibdeleone C show low nM cytotoxicity towards mult...
Gardado en:
| Publicado en: | J Am Chem Soc |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5004353/ https://ncbi.nlm.nih.gov/pubmed/27459345 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b05484 |
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