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Biosynthesis of phlorisovalerophenone and 4-hydroxy-6-isobutyl-2-pyrone in Escherichia coli from glucose

BACKGROUND: Type III polyketide synthases (PKSs) contribute to the synthesis of many economically important natural products, which are typically produced by direct extraction from plants or synthesized chemically. For example, humulone and lupulone (Fig. 1a) in hops (Humulus lupulus) account for th...

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Detalhes bibliográficos
Publicado no:Microb Cell Fact
Main Authors: Zhou, Wei, Zhuang, Yibin, Bai, Yanfen, Bi, Huiping, Liu, Tao, Ma, Yanhe
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004256/
https://ncbi.nlm.nih.gov/pubmed/27577056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-016-0549-9
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