Anti-proliferative and cytotoxic activity of rosuvastatin against melanoma cells

INTRODUCTION: Statins are considered potential candidate agents for melanoma chemoprevention. Statin-induced mevalonate pathway inhibition leads to reduction of cholesterol synthesis and also to decreased cellular levels of non-steroidal isoprenoids, geranylgeranyl pyrophosphate and farnesyl pyropho...

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Bibliographic Details
Published in:Postepy Dermatol Alergol
Main Authors: Maj, Malgorzata, Czajkowski, Rafal, Zegarska, Barbara, Kowaliszyn, Bogna, Pokrywczynska, Marta, Drewa, Tomasz
Format: Artigo
Language:Inglês
Published: Termedia Publishing House 2016
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Original Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004214/
https://ncbi.nlm.nih.gov/pubmed/27605895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5114/ada.2016.61601
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