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Role of Cathepsins in Mycobacterium tuberculosis Survival in Human Macrophages

Cathepsins are proteolytic enzymes that function in the endocytic pathway, especially in lysosomes, where they contribute directly to pathogen killing or indirectly, by their involvement in the antigen presentation pathways. Mycobacterium tuberculosis (MTB) is a facultative intracellular pathogen th...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Pires, David, Marques, Joana, Pombo, João Palma, Carmo, Nuno, Bettencourt, Paulo, Neyrolles, Olivier, Lugo-Villarino, Geanncarlo, Anes, Elsa
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004184/
https://ncbi.nlm.nih.gov/pubmed/27572605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32247
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