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Noggin inactivation affects the number and differentiation potential of muscle progenitor cells in vivo

Inactivation of Noggin, a secreted antagonist of Bone Morphogenetic Proteins (BMPs), in mice leads, among others, to severe malformations of the appendicular skeleton and defective skeletal muscle fibers. To determine the molecular basis of the phenotype, we carried out a histomorphological and mole...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Costamagna, Domiziana, Mommaerts, Hendrik, Sampaolesi, Maurilio, Tylzanowski, Przemko
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004166/
https://ncbi.nlm.nih.gov/pubmed/27573479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31949
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