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In silico modelling of a cancer stem cell-targeting agent and its effects on tumour control during radiotherapy

Head and neck cancers (HNC), like most solid tumours, contain a subpopulation of cancer stem cells (CSC) that are commonly responsible for treatment failure. Conventional therapies are unsuccessful in controlling CSCs, thus novel, targeting therapies are needed. A promising agent is ATRA (All-trans-...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Marcu, Loredana G., Marcu, David
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004146/
https://ncbi.nlm.nih.gov/pubmed/27573059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32332
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