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Icariin Attenuates OGD/R-Induced Autophagy via Bcl-2-Dependent Cross Talk between Apoptosis and Autophagy in PC12 Cells

Icariin (ICA), an active component of Epimedium brevicornum Maxim, exerts a variety of neuroprotective effects such as antiapoptosis. However, the mechanisms underlying antiapoptosis of ICA in neurons exposed to oxygen-glucose deprivation and reperfusion (OGD/R) are unclear. The B-cell lymphoma-2 (B...

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Détails bibliographiques
Publié dans:Evid Based Complement Alternat Med
Auteurs principaux: Mo, Zhen-tao, Li, Wen-na, Zhai, Yu-rong, Gong, Qi-hai
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004044/
https://ncbi.nlm.nih.gov/pubmed/27610184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/4343084
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