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Induction of heat shock proteins in differentiated human neuronal cells following co-application of celastrol and arimoclomol

Few effective therapies exist for the treatment of neurodegenerative diseases that have been characterized as protein misfolding disorders. Upregulation of heat shock proteins (Hsps) mitigates against the accumulation of misfolded, aggregation-prone proteins and synaptic dysfunction, which is recogn...

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Bibliografske podrobnosti
izdano v:Cell Stress Chaperones
Main Authors: Deane, Catherine A. S., Brown, Ian R.
Format: Artigo
Jezik:Inglês
Izdano: Springer Netherlands 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003800/
https://ncbi.nlm.nih.gov/pubmed/27273088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-016-0708-2
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