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Induction of heat shock proteins in differentiated human neuronal cells following co-application of celastrol and arimoclomol

Few effective therapies exist for the treatment of neurodegenerative diseases that have been characterized as protein misfolding disorders. Upregulation of heat shock proteins (Hsps) mitigates against the accumulation of misfolded, aggregation-prone proteins and synaptic dysfunction, which is recogn...

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Publicado en:Cell Stress Chaperones
Autores principales: Deane, Catherine A. S., Brown, Ian R.
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer Netherlands 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003800/
https://ncbi.nlm.nih.gov/pubmed/27273088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-016-0708-2
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