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Induction of heat shock proteins in differentiated human neuronal cells following co-application of celastrol and arimoclomol

Few effective therapies exist for the treatment of neurodegenerative diseases that have been characterized as protein misfolding disorders. Upregulation of heat shock proteins (Hsps) mitigates against the accumulation of misfolded, aggregation-prone proteins and synaptic dysfunction, which is recogn...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Stress Chaperones
Prif Awduron: Deane, Catherine A. S., Brown, Ian R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer Netherlands 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003800/
https://ncbi.nlm.nih.gov/pubmed/27273088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-016-0708-2
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