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New models of hematogenous ovarian cancer metastasis demonstrate preferential spread to the ovary and a requirement for the ovary for abdominal dissemination

Emerging evidence suggest that many high grade serous ‘ovarian’ cancers (HGSOC) start in the fallopian tube. Cancer cells are then recruited to the ovary and then spread diffusely through the abdomen. The mechanism of ovarian cancer spread was thought to be largely due to direct shedding of tumor ce...

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Dettagli Bibliografici
Pubblicato in:Transl Res
Autori principali: Coffman, Lan G, Burgos-Ojeda, Daniela, Wu, Rong, Cho, Kathleen, Bai, Shoumei, Buckanovich, Ronald J
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003680/
https://ncbi.nlm.nih.gov/pubmed/27083386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2016.03.016
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