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New models of hematogenous ovarian cancer metastasis demonstrate preferential spread to the ovary and a requirement for the ovary for abdominal dissemination

Emerging evidence suggest that many high grade serous ‘ovarian’ cancers (HGSOC) start in the fallopian tube. Cancer cells are then recruited to the ovary and then spread diffusely through the abdomen. The mechanism of ovarian cancer spread was thought to be largely due to direct shedding of tumor ce...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Transl Res
Hauptverfasser: Coffman, Lan G, Burgos-Ojeda, Daniela, Wu, Rong, Cho, Kathleen, Bai, Shoumei, Buckanovich, Ronald J
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003680/
https://ncbi.nlm.nih.gov/pubmed/27083386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2016.03.016
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