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Systematic optimization of an engineered hydrogel allows for selective control of human neural stem cell survival and differentiation after transplantation in the stroke brain

Stem cell therapies have shown promise in promoting recovery in stroke but have been limited by poor cell survival and differentiation. We have developed a hyaluronic acid (HA)-based self-polymerizing hydrogel that serves as a platform for adhesion of structural motifs and a depot release for growth...

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Библиографические подробности
Опубликовано в: :Biomaterials
Главные авторы: Moshayedi, Pouria, Nih, Lina R., Llorente, Irene L., Berg, Andrew R., Cinkornpumin, Jessica, Lowry, William E., Segura, Tatiana, Carmichael, S. Thomas
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003628/
https://ncbi.nlm.nih.gov/pubmed/27521617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2016.07.028
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