Intramuscular depot formulations of leuprolide acetate suppress testosterone levels below a 20 ng/dL threshold: a retrospective analysis of two Phase III studies

INTRODUCTION: Androgen deprivation therapy (ADT) with gonadotropin-releasing hormone (GnRH) analogs is a standard treatment for advanced prostate cancer. GnRH analog therapy can reduce testosterone to “castrate” levels, historically defined as <50 ng/dL. With the advent of newer assays, a lower t...

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Detalhes bibliográficos
Publicado no:Res Rep Urol
Main Authors: Spitz, Aaron, Gittelman, Marc, Karsh, Lawrence I, Dragnic, Sanja, Soliman, Ahmed M, Lele, Aditya, Gruca, Damian, Norton, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003568/
https://ncbi.nlm.nih.gov/pubmed/27602344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/RRU.S111475
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