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Hematopoietic stem/progenitor cell commitment to the megakaryocyte lineage

The classical model of hematopoiesis has long held that hematopoietic stem cells (HSCs) sit at the apex of a developmental hierarchy in which HSCs undergo long-term self-renewal while giving rise to cells of all the blood lineages. In this model, self-renewing HSCs progressively lose the capacity fo...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Woolthuis, Carolien M., Park, Christopher Y.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003506/
https://ncbi.nlm.nih.gov/pubmed/26787736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-07-607945
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