Development of 2, 7-Diamino-1, 8-Naphthyridine (DANP) Anchored Hairpin Primers for RT-PCR Detection of Chikungunya Virus Infection

A molecular diagnostic platform with DANP-anchored hairpin primer was developed and evaluated for the rapid and cost-effective detection of Chikungunya virus (CHIKV) with high sensitivity and specificity. The molecule 2, 7-diamino-1, 8-naphthyridine (DANP) binds to a cytosine-bulge and emits fluores...

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Опубликовано в: :PLoS Negl Trop Dis
Главные авторы: Chen, Huixin, Parimelalagan, Mariya, Takei, Fumie, Hapuarachchi, Hapuarachchige Chanditha, Koay, Evelyn Siew-Chuan, Ng, Lee Ching, Ho, Phui San, Nakatani, Kazuhiko, Chu, Justin Jang Hann
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2016
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003370/
https://ncbi.nlm.nih.gov/pubmed/27571201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0004887
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