Engineering of complex protein sialylation in plants

Sialic acids (Sias) are abundant terminal modifications of protein-linked glycans. A unique feature of Sia, compared with other monosaccharides, is the formation of linear homo-polymers, with its most complex form polysialic acid (polySia). Sia and polySia mediate diverse biological functions and ha...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Kallolimath, Somanath, Castilho, Alexandra, Strasser, Richard, Grünwald-Gruber, Clemens, Altmann, Friedrich, Strubl, Sebastian, Galuska, Christina Elisabeth, Zlatina, Kristina, Galuska, Sebastian Peter, Werner, Stefan, Thiesler, Hauke, Werneburg, Sebastian, Hildebrandt, Herbert, Gerardy-Schahn, Rita, Steinkellner, Herta
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2016
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003249/
https://ncbi.nlm.nih.gov/pubmed/27444013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1604371113
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