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Hyaluronic acid-decorated dual responsive nanoparticles of Pluronic F127, PLGA, and chitosan for targeted co-delivery of doxorubicin and irinotecan to eliminate cancer stem-like cells

Dual responsive nanoparticles are developed for co-delivery of multiple anticancer drugs to target the drug resistance mechanisms of cancer stem-like cells (CSCs). The nanoparticles consist of four polymers approved by the Food and Drug Administration (FDA) for medical use: Poly(D,L-lactide-co-glyco...

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Detalhes bibliográficos
Publicado no:Biomaterials
Main Authors: Wang, Hai, Agarwal, Pranay, Zhao, Shuting, Xu, Ronald X., Yu, Jianhua, Lu, Xiongbin, He, Xiaoming
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003084/
https://ncbi.nlm.nih.gov/pubmed/26344365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2015.08.048
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