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Classification of TP53 Mutations and HPV Predict Survival in Advanced Larynx Cancer

OBJECTIVE: Assess TP53 functional mutations in the context of other biomarkers in advanced larynx cancer. STUDY DESIGN: Prospective analysis of pretreatment tumor TP53, HPV, Bcl-xL and cyclin D1 status in stage III and IV larynx cancer patients in a clinical trial. METHODS: TP53 exons 4-9 from 58 tu...

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Detalhes bibliográficos
Publicado no:Laryngoscope
Main Authors: Scheel, Adam, Bellile, Emily, McHugh, Jonathan B., Walline, Heather M., Prince, Mark E., Urba, Susan, Wolf, Gregory T., Eisbruch, Avraham, Worden, Francis, Carey, Thomas E., Bradford, Carol
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5002993/
https://ncbi.nlm.nih.gov/pubmed/27345657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/lary.25915
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