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A commonly-used ecto-ATPase inhibitor, ARL-67156, blocks degradation of ADP more than the degradation of ATP in murine colon

BACKGROUND: Adenosine 5’-triphosphate (ATP) is released extracellularly as a neurotransmitter and an autocrine or paracrine mediator in numerous systems, including the gastrointestinal tract. It is rapidly degraded to active and inactive metabolites by membrane-bound enzymes. Investigators frequentl...

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Detalhes bibliográficos
Publicado no:Neurogastroenterol Motil
Main Authors: Durnin, Leonie, Moreland, Nichola, Lees, Andrea, Mutafova-Yambolieva, Violeta N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5002237/
https://ncbi.nlm.nih.gov/pubmed/27060478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nmo.12836
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