Evaluation of high-dose rifampin in patients with new, smear-positive tuberculosis (HIRIF): study protocol for a randomized controlled trial

BACKGROUND: Evidence has existed for decades that higher doses of rifampin may be more effective, but potentially more toxic, than standard doses used in tuberculosis treatment. Whether increased doses of rifampin could safely shorten treatment remains an open question. METHODS/DESIGN: The HIRIF stu...

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Detalhes bibliográficos
Publicado no:BMC Infect Dis
Main Authors: Milstein, Meredith, Lecca, Leonid, Peloquin, Charles, Mitchison, Denis, Seung, Kwonjune, Pagano, Marcello, Coleman, David, Osso, Elna, Coit, Julia, Vargas Vasquez, Dante Elmo, Sanchez Garavito, Epifanio, Calderon, Roger, Contreras, Carmen, Davies, Geraint, Mitnick, Carole D.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Study Protocol
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5002098/
https://ncbi.nlm.nih.gov/pubmed/27567500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12879-016-1790-x
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