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Direct Observation of the Intrinsic Backbone Torsional Mobility of Disordered Proteins

The fundamental backbone dynamics of unfolded proteins arising due to intrinsic ϕ-ψ dihedral angle fluctuations dictate the course of protein folding, binding, assembly, and function. These internal fluctuations are also critical for protein misfolding associated with a range of human diseases. Howe...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Jain, Neha, Narang, Dominic, Bhasne, Karishma, Dalal, Vijit, Arya, Shruti, Bhattacharya, Mily, Mukhopadhyay, Samrat
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5002086/
https://ncbi.nlm.nih.gov/pubmed/27558720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.07.023
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