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N-sulfation of heparan sulfate is critical for syndecan-4-mediated podocyte cell-matrix interactions

Previous research has shown that podocytes unable to assemble heparan sulfate on cell surface proteoglycan core proteins have compromised cell-matrix interactions. This report further explores the role of N-sulfation of intact heparan chains in podocyte-matrix interactions. For the purposes of this...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Sugar, Terrel, Wassenhove-McCarthy, Deborah J., Orr, A. Wayne, Green, Jonette, van Kuppevelt, Toin H., McCarthy, Kevin J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5002056/
https://ncbi.nlm.nih.gov/pubmed/26936875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00603.2015
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