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Conformational selection and dynamic adaptation upon linker histone binding to the nucleosome

Linker histones are essential for DNA compaction in chromatin. They bind to nucleosomes in a 1:1 ratio forming chromatosomes. Alternative configurations have been proposed in which the globular domain of the linker histone H5 (gH5) is positioned either on- or off-dyad between the nucleosomal and lin...

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Библиографические подробности
Опубликовано в: :Nucleic Acids Res
Главные авторы: Öztürk, Mehmet Ali, Pachov, Georgi V., Wade, Rebecca C., Cojocaru, Vlad
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5001602/
https://ncbi.nlm.nih.gov/pubmed/27270081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw514
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