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Resolvin D2 decreases TLR4 expression to mediate resolution in human monocytes
TLRs are critical for innate immunity, but excessive activation can lead to tissue damage and disease. Specialized proresolving mediators (SPMs), including resolvin D2 (RvD2), promote the active resolution of inflammation. How SPMs regulate early LPS signaling, including activation of TLR4, is unkno...
Enregistré dans:
| Publié dans: | FASEB J |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Federation of American Societies for Experimental Biology
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5001508/ https://ncbi.nlm.nih.gov/pubmed/27256622 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201600375R |
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