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Topic model-based mass spectrometric data analysis in cancer biomarker discovery studies

BACKGROUND: A fundamental challenge in quantitation of biomolecules for cancer biomarker discovery is owing to the heterogeneous nature of human biospecimens. Although this issue has been a subject of discussion in cancer genomic studies, it has not yet been rigorously investigated in mass spectrome...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Wang, Minkun, Tsai, Tsung-Heng, Di Poto, Cristina, Ferrarini, Alessia, Yu, Guoqiang, Ressom, Habtom W.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5001243/
https://ncbi.nlm.nih.gov/pubmed/27535232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2796-x
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