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Integrative analysis of somatic mutations and transcriptomic data to functionally stratify breast cancer patients

BACKGROUND: Somatic mutations can be used as potential biomarkers for subtyping and predicting outcomes for cancer patients. However, cancer patients often carry many somatic mutations, which do not always concentrate on specific genomic loci, suggesting that the mutations may affect common pathways...

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Publicat a:BMC Genomics
Autors principals: Zhang, Jie, Abrams, Zachary, Parvin, Jeffrey D., Huang, Kun
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5001235/
https://ncbi.nlm.nih.gov/pubmed/27556157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2902-0
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