Demethylation treatment restores erectile function in a rat model of hyperhomocysteinemia

Methylation modification is an important cellular mechanism of gene expression regulation. Dimethylarginine dimethylaminohydrolase-2 (DDAH-2) protein is a pivotal molecular for endothelium function. To explore the effects of 5-aza-deoxycytidine (5-aza), a demethylation agent, in hyperhomocysteinemia...

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Bibliographic Details
Published in:Asian J Androl
Main Authors: Zhang, Zheng, Zhu, Lei-Lei, Jiang, He-Song, Chen, Hai, Chen, Yun, Dai, Yu-Tian
Format: Artigo
Language:Inglês
Published: Medknow Publications & Media Pvt Ltd 2016
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5000801/
https://ncbi.nlm.nih.gov/pubmed/26585696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1008-682X.163271
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