In vivo and in vitro degradation of peptide YY(3–36) to inactive peptide YY(3–34) in humans

Peptide YY (PYY) is a 36-amino-acid peptide released from enteroendocrine cells upon food intake. The NH(2) terminally truncated metabolite, PYY(3–36), exerts anorexic effects and has received considerable attention as a possible antiobesity drug target. The kinetics and degradation products of PYY...

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Vydáno v:Am J Physiol Regul Integr Comp Physiol
Hlavní autoři: Toräng, Signe, Bojsen-Møller, Kirstine Nyvold, Svane, Maria Saur, Hartmann, Bolette, Rosenkilde, Mette Marie, Madsbad, Sten, Holst, Jens Juul
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2016
Témata:
Obesity, Diabetes and Energy Homeostasis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5000776/
https://ncbi.nlm.nih.gov/pubmed/26818056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00394.2015
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