25(OH)D Is Effective to Repress Human Cholangiocarcinoma Cell Growth through the Conversion of 25(OH)D to 1α,25(OH)(2)D(3)

Cholangiocarcinoma (CCA) is a devastating disease without effective treatments. 1α,25(OH)(2)D(3), the active form of Vitamin D, has emerged as a new anti-cancer regimen. However, the side effect of hypercalcemia impedes its systemic administration. 25(OH)D is biologically inert and needs hydroxylati...

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Udgivet i:Int J Mol Sci
Main Authors: Chiang, Kun-Chun, Yeh, Chun-Nan, Huang, Cheng-Cheng, Yeh, Ta-Sen, S. Pang, Jong-Hwei, Hsu, Jun-Te, Chen, Li-Wei, Kuo, Sheng-Fong, Kittaka, Atsushi, Chen, Tai C., Juang, Horng-Heng
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5000723/
https://ncbi.nlm.nih.gov/pubmed/27529229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17081326
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