Propofol Anesthesia Induces Proapoptotic Tumor Necrosis Factor-α and Pro-Nerve Growth Factor Signaling and Prosurvival Akt and XIAP Expression in Neonatal Rat Brain

Previously we observed that prolonged exposure to propofol anesthesia causes caspase-3- and calpain-mediated neuronal death in the developing brain. The present study examines the effects of propofol anesthesia on the expression of tumor necrosis factor-α (TNFα), pro-nerve growth factor (NGF), and t...

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Gepubliceerd in:J Neurosci Res
Hoofdauteurs: Milanović, Desanka, Pešić, Vesna, Popić, Jelena, Tanić, Nikola, Kanazir, Selma, Jevtović-Todorović, Vesna, Ruždijić, Sabera
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5000575/
https://ncbi.nlm.nih.gov/pubmed/24827783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.23409
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