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Evidence for biased agonists and antagonists at the endothelin receptors

Biased ligands represent a new strategy for the development of more effective and better tolerated drugs. To date there has been a paucity of research exploring the potential of ligands that exhibit either G protein or β-arrestin pathway selectivity at the endothelin receptors. Re-analysis of data m...

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Detalhes bibliográficos
Publicado no:Life Sci
Autor principal: Maguire, Janet J.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5000545/
https://ncbi.nlm.nih.gov/pubmed/26898124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2016.02.069
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