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Liver-specific Gene Inactivation of the Transcription Factor ATF4 Alleviates Alcoholic Liver Steatosis in Mice

Although numerous biological functions of the activating transcription factor 4 (ATF4) have been identified, a direct effect of ATF4 on alcoholic liver steatosis has not been described previously. The aim of our current study is to investigate the role of ATF4 in alcoholic liver steatosis and elucid...

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Publicado en:J Biol Chem
Autores principales: Li, Kai, Xiao, Yuzhong, Yu, Junjie, Xia, Tingting, Liu, Bin, Guo, Yajie, Deng, Jiali, Chen, Shanghai, Wang, Chunxia, Guo, Feifan
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5000098/
https://ncbi.nlm.nih.gov/pubmed/27405764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.726836
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